References

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References & Information

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A. Terenji, S. Willmann, J. Osterholz, P. Hering, and H. J. Schwarzmaier. Measurement of the coagulation dynamics of bovine liver using the modified microscopic Beer-Lambert law. Lasers Surg Med. 365-70. 36(5). 2005.

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K. Thelen, E. Jantratid, J. B. Dressman, J. Lippert, and S. Willmann. Analysis of nifedipine absorption from soft gelatin capsules using PBPK modeling and biorelevant dissolution testing. J Pharm Sci. 2899-904. 99(6). 2010.

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K. Thelen, K. Coboeken, S. Willmann, R. Burghaus, J. B. Dressman, and J. Lippert. Evolution of a detailed physiological model to simulate the gastrointestinal transit and absorption process in humans, part 1: oral solutions. J Pharm Sci. 5324-45. 100(12). 2011.

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M. Vossen, M. Sevestre, C. Niederalt, I. J. Jang, S. Willmann, and A. N. Edginton. Dynamically simulating the interaction of midazolam and the CYP3A4 inhibitor itraconazole using individual coupled whole-body physiologically-based pharmacokinetic (WB-PBPK) models. Theor Biol Med Model. 13. 4. 2007.

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S. Willmann, A. Terenji, H. Busse, I. V. Yaroslavsky, A. N. Yaroslavsky, H. J. Schwarzmaier, and P. Hering. Scattering delay time of Mie scatterers determined from steady-state and time-resolved optical spectroscopy. J Opt Soc Am A Opt Image Sci Vis. 745-9. 17(4). 2000.

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S. Willmann, W. Schmitt, J. Keldenich, and J. B. Dressman. A Physiologic Model for Simulating Gastrointestinal Flow and Drug Absorption in Rats. Pharmaceutical Research. 20. 1766-1771. 2003.

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S. Willmann, A. Terenji, J. Osterholz, J. Meister, P. Hering, and H.J. Schwarzmaier. Small-volume frequency-domain oximetry: phantom experiments and first in vivo results. J Biomed Opt. 618-28. 8(4). 2003.

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S. Willmann, W. Schmitt, J. Keldenich, J. Lippert, and J. B. Dressman. A Physiological Model for the Estimation of Fraction Dose Absorbed in Humans. Journal of Medical Chemistry. 47. 4022-4031. 2004.

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S. Willmann, J. Lippert, and W. Schmitt. From physicochemistry to absorption and distribution: predictive mechanistic modelling and computational tools. Expert Opinion on Drug Metabolism and Toxicology. 1. 159-168. 2005.

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S. Willmann, K. Hoehn, A. N. Edginton, M. Sevestre, J. Solodenko, W. Weiss, J. Lippert, and W. Schmitt. Development of a physiologically-based whole-body population model for assessing the influence of individual variability on the pharmacokinetics of drugs. Journal of Pharmacokinetics and Pharmacodynamics. 34(3). 401-431. 2007.

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S. Willmann, A.N. Edginton, and J.B. Dressman. Development and validation of a physiology-based model for the prediction of oral absorption in monkeys. Pharmaceutical Research. 24(7). 1275-82. 2007.

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S. Willmann, A.N. Edginton, M. Kleine-Besten, E. Jantratid, K. Thelen, and J.B. Dressman. Whole-Body Physiologically-Based Pharmacokinetic Population Modelling of Oral Drug Administration: Inter-Individual Variability of Cimetidine Absorption. Journal of Pharmacokinetics and Pharmacodynamics. 61. 891-9. 2009.

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S. Willmann, A.N. Edginton, K. Coboeken, G. Ahr, and J. Lippert. Risk to the Breast-Fed Neonate From Codeine Treatment to the Mother: A Quantitative Mechanistic Modeling Study. Clinical Pharmacology and Therapeutics. advance online publication. 2009.

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S. Willmann. The in silico Child. Can computer simulations replace clinical pharmacokinetic studies?. Original: Das In-silico-Child. Konnen Computer-Simulationen klinisch-pharmakokinetische Studien ersetzen?. Pharm Unserer Zeit. 62-7. 38(1). 2009.

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S. Willmann, K. Thelen, C. Becker, J. B. Dressman, and J. Lippert. Mechanism-based prediction of particle size-dependent dissolution and absorption: cilostazol pharmacokinetics in dogs. Eur J Pharm Biopharm. 83-94. 76(1). 2010.

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Y. Wu and F. Kesisoglou. Immediate Release Oral Dosage Forms: Formulation Screening in the Pharmaceutical Industry. in: Oral Drug Absorption: Prediction and Assessment. J. J. Dressman. C. Reppas. Informa Healthcare. New York, USA. pp. 323. 2009.

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J. Yang, M. Jamei, and K. Rowland Yeo. Theoretical assessment of a new experimental protocol for determining kinetic values describing mechanism (time)-based enzyme inhibition . European Journal in Pharmaceutical Sciences. 31. 2007.

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H. Zischka, C. J. Gloeckner, C. Klein, S. Willmann, M. Swiatek-de Lange, and M. Ueffing. Improved mass spectrometric identification of gel- separated hydrophobic membrane proteins after sodium dodecyl sulfate removal by ion-pair extraction. Proteomics. 3776-82. 4(12). 2004.