Open Systems Pharmacology
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README
Open Systems Pharmacology Suite Manual & Copyright
How to Contribute
Mechanistic Modeling of Pharmacokinetics and Dynamics
Modeling Concepts
Open Systems Pharmacology Suite
Modules, Philosophy, and Building Blocks
Getting Started
Working with PK-Sim
PK-Sim Documentation
Quick Guide‌
Options
Projects
Creating Individuals
Creating Populations
Expression Profile
Compounds: Definition and Work Flows
Compounds: Defining Inhibition/Induction Processes
Administration Protocols
Events
Formulations
Simulations
Importing and Exporting Project Data and Models
Conversion of Projects from Previous Version
Command Line Interface - CLI
Working with MoBi
MoBi‌ Documentation
Shared Tools and Example Workflows
Features of Tables
Chart Component
Comparison of Building Blocks
Parameter Identification
Sensitivity Analysis
Import and Edit of Observed Data
Default, Display and Base Units
Working Journal
History Manager and History Reporting‌
Setting up a Reaction Network‌
Setting up a Drug-Drug Interaction in PK-Sim‌
Qualification‌
Working with R‌
ospsuite-R Documentation
Appendix
Appendix
OSP Suite Fact Sheet
References
References
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Quick Guide‌
Here, only the basic steps needed to work with a PBPK simulation in PK-Sim® are briefly described (creation of a model, comparison of simulation data to observed data and refinement of the model):
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Working with PK-Sim - Previous
PK-Sim Documentation
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