Open Systems Pharmacology
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Introduction
Open Systems Pharmacology Suite Manual & Copyright
How to Contribute
Mechanistic Modeling of Pharmacokinetics and Dynamics
Modeling Concepts
Open Systems Pharmacology Suite
Modules, Philosophy, and Building Blocks
Getting Started
Working with PK-Sim
PK-Sim Documentation
Working with MoBi
MoBi‌ Documentation
Shared Tools and Example Workflows
Features of Tables
Chart Component
Comparison of Building Blocks
Parameter Identification
Sensitivity Analysis
Import and Edit of Observed Data
Default, Display and Base Units
Reporting
Working Journal
History Manager and History Reporting‌
Setting up a Reaction Network‌
Setting up a Drug-Drug Interaction in PK-Sim‌
Qualification‌
Working with R‌
ospsuite-R Documentation
Appendix
Appendix
OSP Suite Fact Sheet
References
References
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Open Systems Pharmacology Suite Manual & Copyright
Version 10
Publication date October 2021
The manual is provided “as is” without expressed or implied warranty.
Trademark information:
All trademarks within this manual belong to their legitimate owners.
The Open Systems Pharmacology Suite uses the CVODES solver:
Copyright (c) 2002-2021, Lawrence Livermore National Security. Produced at the Lawrence Livermore National Laboratory. Written by A.C. Hindmarsh, D.R. Reynolds, R. Serban, C.S. Woodward, D. J. Gardner, S.D. Cohen, A.G. Taylor, S. Peles, L.E. Banks, and D. Shumaker. UCRL-CODE-155950 (CVODES) All rights reserved.
Please, refer to the LLNL website for detailed information on licensing:
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