Open Systems Pharmacology
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  • README
  • Open Systems Pharmacology Suite Manual & Copyright
  • How to Contribute
  • Mechanistic Modeling of Pharmacokinetics and Dynamics
    • Best Practices
      • Introduction
      • Model Development
      • Model Evaluation
      • Application Simulation
      • Documentation
    • Modeling Concepts
      • PBPK Modeling - Systems Biology
      • PK and PD Modeling
      • Principles of PBPK Modeling
      • Expression Data for PBPK Modeling
      • Modeling of Proteins
      • PD and Reaction Network Modeling
  • Open Systems Pharmacology Suite
    • Modules, Philosophy, and Building Blocks
    • Getting Started
  • Working with PK-Sim
    • PK-Sim Documentation
      • Quick Guide‌
      • Options
      • Projects
      • Creating Individuals
      • Creating Populations
      • Expression Profile
      • Compounds: Definition and Work Flows
      • Compounds: Defining Inhibition/Induction Processes
      • Administration Protocols
      • Events
      • Formulations
      • Simulations
      • Importing and Exporting Project Data and Models
      • Conversion of Projects from Previous Version
      • Command Line Interface - CLI
  • Working with MoBi
    • MoBi‌ Documentation
      • First Steps
      • The Building Block Concept
      • Model Building and Model Components
      • Setting up a Simulation
      • Simulation Results
      • Diagrams Overview
      • Tools
      • Reuse of Project Information from Previous Versions
  • Shared Tools and Example Workflows
    • Features of Tables
    • Chart Component
    • Comparison of Building Blocks
    • Parameter Identification
    • Sensitivity Analysis
    • Import and Edit of Observed Data
    • Default, Display and Base Units
    • Working Journal
    • History Manager and History Reporting‌
    • Setting up a Reaction Network‌
    • Setting up a Drug-Drug Interaction in PK-Sim‌
    • Qualification‌
  • Working with R‌
    • ospsuite-R Documentation
    • Reporting Engine (RE)
    • TLF Library
  • Appendix
    • Appendix
    • OSP Suite Fact Sheet
  • References
    • References
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