Open Systems Pharmacology
ForumSetup
v10
v10
  • Introduction
  • Open Systems Pharmacology Suite Manual & Copyright
  • How to Contribute
  • Mechanistic Modeling of Pharmacokinetics and Dynamics
    • Modeling Concepts
      • PBPK Modeling - Systems Biology
      • PK and PD Modeling
      • Principles of PBPK Modeling
      • Expression Data for PBPK Modeling
      • Modeling of Proteins
      • PD and Reaction Network Modeling
  • Open Systems Pharmacology Suite
    • Modules, Philosophy, and Building Blocks
    • Getting Started
  • Working with PK-Sim
    • PK-Sim Documentation
      • Quick Guide‌
      • Options
      • Projects
      • Creating Individuals
      • Creating Populations
      • Expression Data
      • Compounds: Definition and Work Flows
      • Compounds: Defining Inhibition/Induction Processes
      • Administration Protocols
      • Events
      • Formulations
      • Simulations
      • Importing and Exporting Project Data and Models
      • Conversion of Projects from Previous Version
      • Command Line Interface - CLI
  • Working with MoBi
    • MoBi‌ Documentation
      • First Steps
      • The Building Block Concept
      • Model Building and Model Components
      • Setting up a Simulation
      • Simulation Results
      • Diagrams Overview
      • Tools
      • Reuse of Project Information from Previous Versions
  • Shared Tools and Example Workflows
    • Features of Tables
    • Chart Component
    • Comparison of Building Blocks
    • Parameter Identification
    • Sensitivity Analysis
    • Import and Edit of Observed Data
    • Default, Display and Base Units
    • Reporting
    • Working Journal
    • History Manager and History Reporting‌
    • Setting up a Reaction Network‌
    • Setting up a Drug-Drug Interaction in PK-Sim‌
    • Qualification‌
  • Working with R‌
    • ospsuite-R Documentation
  • Appendix
    • Appendix
    • OSP Suite Fact Sheet
  • References
    • References
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  • Reuse of MoBi® 2 projects in MoBi® 3‌
  • Conversion of MoBi® 3.1 projects.
  1. Working with MoBi
  2. MoBi‌ Documentation

Reuse of Project Information from Previous Versions

PreviousToolsNextFeatures of Tables

Last updated 3 years ago

Reuse of MoBi® 2 projects in MoBi® 3‌

MoBi® 2 projects are not supported any more.

Conversion of MoBi® 3.1 projects.

Projects created with MoBi® 3.1 are automatically converted when opened.

In MoBi® 3.1 in some cases it was necessary to insert manual conversion factors into formulas, if dimensions with inconsistent base units were used. In the current version such conversion factors are not longer necessary.

If you have inserted such manual conversion factors, you have to eliminate those factors and to rebuild the simulations to get proper simulation results. Please perform the following steps to identify and remove manual conversion factors and to rebuild the simulations.

  1. Open the project stored from MoBi® 3.1.

  2. Open the Notifications view, which is autohidden at the bottom by default.

  3. Double click each row with message "Dimension check warning".

    The corresponding formula is opened. Remove any manual conversion factors (mostly powers of 10), if available. Do not remove other factors.

  4. Rebuild each simulation of interest, i.e. build a new simulation with the same building blocks and use the same simulation settings and modifications as in the corresponding old simulation.

  5. Run each new simulation and compare the results. In case of differences check the formulas with "Dimension check warning" again. In case you have to adjust a formula rebuild the simulation again. Otherwise compare carefully the used building blocks, simulation settings and simulation parameter modifications. If you still get different results, please contact our support ().

  6. If you successfully managed to rebuild the simulations with the same results, remove the old simulations from the project. (Due to the conversion factors still contained in those simulations you would produce wrong results running the old simulations with the new version of MoBi.)

http://forum.open-systems-pharmacology.org/