> For the complete documentation index, see [llms.txt](https://docs.open-systems-pharmacology.org/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://docs.open-systems-pharmacology.org/mechanistic-modeling-of-pharmacokinetics-and-dynamics.md).

# Mechanistic Modeling of Pharmacokinetics and Dynamics

- [Best Practices](https://docs.open-systems-pharmacology.org/mechanistic-modeling-of-pharmacokinetics-and-dynamics/best-practices.md)
- [Introduction](https://docs.open-systems-pharmacology.org/mechanistic-modeling-of-pharmacokinetics-and-dynamics/best-practices/a-short-guide-to-pbpk-model-development.md)
- [Model Development](https://docs.open-systems-pharmacology.org/mechanistic-modeling-of-pharmacokinetics-and-dynamics/best-practices/model-development.md)
- [Model Evaluation](https://docs.open-systems-pharmacology.org/mechanistic-modeling-of-pharmacokinetics-and-dynamics/best-practices/model-evaluation.md)
- [Application Simulation](https://docs.open-systems-pharmacology.org/mechanistic-modeling-of-pharmacokinetics-and-dynamics/best-practices/application-simulation.md)
- [Documentation](https://docs.open-systems-pharmacology.org/mechanistic-modeling-of-pharmacokinetics-and-dynamics/best-practices/documentation.md)
- [Modeling Concepts](https://docs.open-systems-pharmacology.org/mechanistic-modeling-of-pharmacokinetics-and-dynamics/modeling-concepts.md)
- [PBPK Modeling - Systems Biology](https://docs.open-systems-pharmacology.org/mechanistic-modeling-of-pharmacokinetics-and-dynamics/modeling-concepts/modeling-concepts-pbpk-modeling-systems-biology.md)
- [PK and PD Modeling](https://docs.open-systems-pharmacology.org/mechanistic-modeling-of-pharmacokinetics-and-dynamics/modeling-concepts/modeling-concepts-pk-and-pd-modeling.md)
- [Principles of PBPK Modeling](https://docs.open-systems-pharmacology.org/mechanistic-modeling-of-pharmacokinetics-and-dynamics/modeling-concepts/principles-of-pbpk-modeling.md)
- [Expression Data for PBPK Modeling](https://docs.open-systems-pharmacology.org/mechanistic-modeling-of-pharmacokinetics-and-dynamics/modeling-concepts/modeling-concepts-expression-data-for-pbpk-modeling.md)
- [Modeling of Proteins](https://docs.open-systems-pharmacology.org/mechanistic-modeling-of-pharmacokinetics-and-dynamics/modeling-concepts/modeling-concepts-modeling-of-proteins.md)
- [PD and Reaction Network Modeling](https://docs.open-systems-pharmacology.org/mechanistic-modeling-of-pharmacokinetics-and-dynamics/modeling-concepts/modeling-concepts-pd-and-reaction-network-modeling.md)